The Choice for Saving Lives

Posts Tagged ‘PSA’

10 Myths and Misconceptions About Prostate Cancer

Tuesday, May 24th, 2011

With the identification of more than 25 types of prostate cancer by PCF-funded scientists in the past 24 months, and the fact that it remains one of the least talked about cancers, it’s no wonder there remains a great deal of confusion surrounding this disease.

Ask any group of men about prostate cancer. If they don’t abruptly change the subject or take the opportunity to crack a few wise remarks, chances are you will get a wide variety of answers when it comes to what it is, how it should be treated and whether or not (and when) one should be screened for this disease. Against this reality, it is always a good idea to review some of the more popular myths and misconceptions about this disease that claims the lives of more than 32,000 men in the U.S. each year.

Myth #1: Prostate cancer is an old man’s disease.

While it may be true that the older you are, the more likely you are to be diagnosed with prostate cancer (65% of cases are diagnosed in men who are 65 or older), the fact remains that 35% of those diagnosed, or more than 76,000 each year, are diagnosed at an earlier age. I was diagnosed at age 51 and I have met many men who were diagnosed in their early 40s. Although only 1 in 10,000 men under age 40 will be diagnosed, the rate skyrockets up to 1 in 38 for ages 40 to 59, and 1 in 15 for ages 60 to 69.

There are many risk factors to consider. Your race, family history, physical health and lifestyle—even geographic location—are all factors that can increase your likelihood of developing prostate cancer.

Myth #2: If you don’t have any symptoms, you don’t have prostate cancer.

Wrong. Prostate cancer is one of the most asymptomatic cancers in oncology, meaning not all men experience symptoms. Many times symptoms can be mistaken or attributed to something else. Signs of prostate cancer are often first detected by a doctor during a routine check-up. Common symptoms include a need to urinate frequently, difficulty starting or stopping urination, weak or interrupted flow of urination, painful or burning urination, difficulty having an erection, painful ejaculation, blood in the urine or semen, or frequent pain and stiffness in the lower back, hips or upper thighs. If you experience any of these symptoms, be sure to tell your doctor.

Myth #3:  Prostate cancer is a slow growing cancer I don’t need to worry about.

The answer to this one is sometimes, yes. Sometimes, no. With the 25 types of prostate cancer discovered by PCF-supported researchers, we can confirm that there are those prostate cancers a man may die with and not of, while others are very aggressive. Once a biopsy confirms the presence of cancer in the prostate, a physician uses the data contained in the pathologist’s report to characterize the potential aggressiveness of the cancer and make recommendations for treatment based on many factors, including a patient’s age and health status. There are many treatments available for patients and one approach does not fit all cases. Patients need to understand the complexity of this disease and make treatment decisions that are right for them in consultation with a trusted medical professional.

The good news is that we believe, with the accelerated pace of scientific discovery, we will soon be able to identify the specific cancer a patient has at time of their diagnosis and match the most effective treatments for their prostate cancer and their biological makeup. This will enable us to cure more and overtreat less.

Myth #4:  Prostate cancer doesn’t run in my family, so the odds aren’t great that I will get it.

Wrong. While a family history of prostate cancer doubles a man’s odds of being diagnosed to 1 in 3, the fact remains that 1 out of 6 American men will be diagnosed with prostate cancer in their lifetime. This compares to 1 in 8 women who will be diagnosed with breast cancer. African-American men are 60% more likely to be diagnosed with prostate cancer and 2.4 times more likely to die as a result.

Family history and genetics do, however, play a role in a man’s chances for developing prostate cancer. A man whose father or bother had prostate cancer is twice as likely to develop the disease. The risk is further increased if the cancer was diagnosed in a family member at a younger age (less than 55 years old), or if it affected three or more family members.

In 2010, approximately 218,000 new cases were diagnosed in the U.S. and more than 32,000 men died as a result of this cancer. The number of new U.S. cases could exceed 300,000 per year by 2015.

Myth #5:  The PSA test is cancer test.

Incorrect. The PSA tests measures levels of prostate-specific antigen in the prostate, not cancer. PSA is produced by the prostate in response to a number of problems that could be present in the prostate including an inflammation or infection (prostatitis), enlargement of the prostate gland (benign prostatic hyperplasia) or, possibly, cancer. Think of it as a first alert smoke alarm, instead of a fire alarm. The PSA test is the first step in the diagnostic process for cancer. It has made detection of cancer in its early stages, when it is best treated, possible. Experts believe the PSA test saves the life of approximately 1 in 39 men who are tested. Personally, I believe the PSA test saved my life and will continue to save it as we track my response to treatment.

Myth #6: A high PSA level means that you have prostate cancer and a low PSA means you do not have prostate cancer.

Although prostate cancer is a common cause of elevated PSA levels, some men with prostate cancer may even have low levels of PSA. PSA can also be diluted in men who are overweight or obese, due to a larger blood volume, and a biopsy should be considered at a relatively lower number (i.e. 3.5 instead of 4). Again, elevated levels can be an indication of other medical conditions.

Myth #7:  Vasectomies cause prostate cancer.

Having a vasectomy was once thought to increase a man’s risk. This issue has since been carefully researched by epidemiologists. Vasectomy has not been linked to increasing a man’s chance of getting prostate cancer but has led to the prostate being checked by the urologist more often and prostate cancer consequently being detected in the clinic.

Myth #8: Treatment for prostate cancer always causes impotence or incontinence.

While erectile dysfunction (ED) and urinary incontinence are possibilities following surgery or radiation therapy for prostate cancer, it is not true that all men experience complications. These side effects can also be highly dependent on age and physical condition. Numerous therapies and aids can improve erectile function and limit incontinence following treatment and nerve sparing surgical procedures have improved outcomes for patients as well. When selecting a surgeon, patients should inquire about the surgeon’s outcomes for ED and incontinence as well as the number of surgical procedures (open or robotic) performed.

Myth #9: Sexual activity increases the risk of developing prostate cancer.

High levels of sexual activity or frequent ejaculation were once rumored to increase prostate cancer risk. In fact, some studies show that men who reported more frequent ejaculations had a lower risk of developing prostate cancer. Ejaculation itself has not been linked to prostate cancer.

Myth #10: You can pass your cancer to others.

Prostate cancer is not infectious or communicable. This means that there is no way for you to “pass it on” to someone else.

What men can do about prostate cancer.

The first step in dealing effectively with prostate cancer is knowing the facts and eliminating confusion. Recent studies have shown that lifestyle decisions such as maintaining a healthy diet and regular exercise, such as walking 30 minutes a day, may also play a pivotal role in reducing the risk of getting prostate cancer and surviving it if you get the disease. Talk to your family and friends about prostate cancer and, if you are over 40, talk to your physician to develop a prostate health and screening plan that is right for you.
By Dan Zenka

From: http://www.pcf.org/site/c.leJRIROrEpH/b.7425707/k.7A02/10_Myths_and_Misconceptions_About_Prostate_Cancer.htm?msource=may11adv&auid=8373209

Prostate Cancer Symposium

Thursday, March 24th, 2011

ATLANTA – As a culmination of the efforts behind the Prostate Cancer Awareness Pledge Campaign, there will be a prostate cancer symposium on Saturday, April 2, 2011 held at the Morehouse School of Medicine located at 720 Westview Drive SW, Atlanta, GA 30310 from 10 a.m. until 3 p.m.

Prostate cancer is a serious health concern in Georgia.  According to the American Cancer Society, the state of Georgia ranks 11th in number of estimated deaths per capita from the disease. 

The Georgia Prostate Cancer Coalition, RC Cancer Centers, Atlanta Hawks, Atlanta Thrashers, UPS, CR Bard, WXIA Television, Morehouse School of Medicine, KISS 104.1 Radio and WSB Radio partnered in support of the challenge for 10,000 men in Georgia pledge to have the conversation with their doctors and/or be screened by April 30, 2011.

The campaign launched in December with a gathering of partners and officials with Mayor Kasim Reed as he signed a pledge card to have a conversation with his doctor and/or be screened for prostate cancer. On Monday, March 14, 2011, legislators from the Georgia House and Senate gathered to sign pledges and got screened for prostate cancer as they recognized Prostate Cancer Awareness Day at the capitol.

“We’ve made great strides in the last few months but still have a ways to go in the mission to raise awareness about prostate cancer in Georgia,” said Frank Catroneo from the Georgia Prostate Cancer Coalition.

The Prostate Cancer Symposium will be divided into two sessions. The morning session for physicians only will begin at 7:30 a.m. and features a panel discussion on public health trends, informed decision making for prostate cancer, outcomes and the impact of health policy impact on prostate cancer. Attending physicians will be eligible for CME credits.

The second session which begins at 10 a.m., is free to the public and will educate and empower men, providing information to support better prostate cancer treatment decision making and raise general awareness. Moderated by Jerry Carnes of WXIA 11 Alive, the day’s program includes several renowned speakers including Jonathan Simons, M.D., president and CEO of the Prostate Cancer Foundation, James Bennett, M.D., Morehouse School of Medicine faculty, Ingrid Hill, Ph.D., MPH from the Centers for Disease Control and Prevention as well as James Benton, M.D., radiation oncologist from RC Cancer Centers.

The Georgia Department of Community Health reports prostate cancer is the leading cause of cancer among Georgia males and accounts for 28 percent of all new cancer cases among males each year. Other than skin cancer, prostate cancer is the most common cancer in American men and the second leading cause of cancer death, behind lung cancer according to the American Cancer Society.

A prostate screening PSA (Prostate Specific Antigen) is a simple blood test which will not define a man’s prostate cancer status, but provides the basis for men to start the right conversations with their doctor.  When prostate cancer is detected early, it is a very curable disease.

“Maintaining an ongoing relationship with our healthcare providers is an essential part of preventive care when discussing prostate cancer because risks vary from person to person,” said Dr. Roland Matthews, from Morehouse School of Medicine and Director of the Grady Cancer Center for Excellence.

“As the campaign continues through the next few weeks,” said Michael Holton, president and COO of RC Cancer Centers. “RC Cancer Centers continues to offer free of charge PSA screenings for men over 40 years old. They can be screened at any one of our five locations in Georgia.  For screening locations, visit www.GeorgiaProstateCancerPledge.com .”

Nationally, about one in six men will be diagnosed with prostate cancer during their lifetime. Prostate cancer is treatable when caught early.

To register for the Prostate Cancer Symposium visit www.GeorgiaProstateCancerPledge.com  or contact Shelly Glenn at 770-682-2099 x. 119 or sglenn@rccancercenters.com.

To learn more about the Prostate Cancer Pledge Campaign, visit www.GeorgiaProstateCancerPledge.com.

Treatment is a Complex Issue

Tuesday, March 22nd, 2011

As a patient, I feel for anyone who is given a diagnosis of prostate cancer.  Hearing the “Big-C” word can be upsetting enough. But the complexity of the disease—diagnosing it, trying to characterize it and selecting the appropriate treatment—can feel like insult upon injury.  We need to talk about prostate cancers. With 24 known sub-types of this cancer—from non-life-threatening to very aggressive—it’s no wonder so much time is expended on debating PSA screening and the potential for overtreatment.

While debates continue, more than 32,000 American men die from this disease each year, placing it on par with breast cancer in incidence and mortality.

Oddly, I still contend that when I was diagnosed last year, I was “lucky” enough to have clear diagnostic and prognostic data to inform my decision to have a radical prostatectomy, despite potential side effects .  My PSA had nearly doubled in a year’s time. As my urologist reviewed my biopsy results, the extent of the cancer’s involvement in my walnut-sized gland and my Gleason scores, I knew where I was headed. He dutifully began sketching out all treatment options currently available to patients when I told him to stop and move to the top two options. He gave me a dubious look before I shared with him that I had learned much about the disease in two years of working at the Prostate Cancer Foundation.

I was lucky once again when my surgeon’s professional instincts prompted him to remove some of my lower lymph nodes during my robotic procedure, something that’s not always done.  The post-surgical pathology report upgraded my diagnosis to Stage 4 metastatic disease with single Gleason 5 cells discovered in the nodes. (Not exactly the kind of upgrades I am accustomed to in my life…) As a result, I headed into seven weeks of radiation therapy and three years of androgen deprivation therapy—a palliative treatment that drastically cuts my production of testosterone, a fuel for prostate cancer growth and proliferation.  Today, I have a 60 percent chance that I will have to live with recurrent disease. I look forward without second guessing.

Not all patients have such clarity. Through My New York Minute, I meet many readers who are confused by the complexity of this disease. As a fellow patient who also works for world’s leading private accelerator of prostate cancer research, I remind them:

  1. The PSA test is not a cancer test—it’s a diagnostic tool for identifying potential problems, including cancer, in the prostate
  2. With 24 sub-types of this cancer, one size does not fit all for treatment
  3. Sometimes, the best treatment is no treatment and proactive surveillance
  4. Age and personal preference are important factors in treatment selection
  5. Once committed to a treatment plan, avoid the pitfall of second guessing

Science will someday, sooner than later, enable us to identify which prostate cancer a patient has and prescribe highly personalized treatments that will work best for their case. Until then, an in-depth understanding of the disease and the advice of a trusted healthcare professional remain the best tools for making treatment decisions with confidence.

From: http://mynewyorkminute.org/?p=1242&utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+MyNewYorkMinute+%28My+New+York+Minute%29

Atlanta Leaders Come Together To Launch Prostate Cancer Pledge Campaign

Tuesday, December 7th, 2010

Prostate cancer is a serious health concern in Georgia.  According to the American Cancer Society, the state of Georgia ranks 11th in number of estimated deaths per capita from the disease.  In an effort to raise awareness about prostate cancer and ensure more men commit to be informed and screened, several companies and media organizations have joined the Georgia Prostate Cancer Coalition in launching a pledge campaign.

The Georgia Prostate Cancer Coalition, RC Cancer Centers and the Georgia Department of Community Health along with the Atlanta  Hawks, Atlanta Thrashers, UPS, CR Bard, WXIA Television, Morehouse School of Medicine, KISS 104.1 Radio and WSB Radio are supporting this initiative to increase prostate cancer awareness throughout the state of Georgia.

“Specifically, we are encouraging every man who is over the age of 40 in Georgia to speak to his doctor and take the pledge to get screened for prostate cancer,” said Frank Catroneo,  Georgia Prostate Cancer Coalition Board Member.  “Our goal is to have 10,000 men in Georgia pledge to have the conversation with their doctors and/or be screened between now and April 20, 2011.”

M. Rony Francois, MD, MSPH, PhD, Director, DCH Division of Public Health and State Health Officer said, “I look forward to the potential that this pledge campaign holds in increasing the number of men who talk to their doctor about prostate cancer screening.”

To encourage prostate cancer discussions and screenings, the Atlanta Hawks and the Georgia Prostate Cancer Pledge committee will provide two tickets to several Atlanta Hawks home games, starting with the December 7th home game versus the New Jersey Nets, to the first 2,000 men who commit to being screened for the first time. Men can visit http://www.hawks.com/ or http://www.georgiaprostatecancerpledge.com/ to make their screening pledge and redeem their complimentary tickets online.

There will be a number of activities and events to help educate men and their loved ones, and to bring awareness to the serious health impact of prostate cancer for all concerned.  The events will culminate in April with a prostate cancer symposium, a golf tournament, a motorcycle ride, video testimonials of survivors and much more.

Michael Holton, president and COO of RC Cancer Centers, which specializes in the ProstRcision treatment for prostate cancer said, “Throughout the campaign, we will be offering free of charge PSA screenings for men over 40 years old, who have not been diagnosed with prostate cancer or previously treated for this disease. They can be screened at any one of our five locations in Georgia.  For screening locations, visit http://www.rccancercenters.com/.”

 Current data available from Georgia Department of Community Health, the Centers for Disease Control and the American Cancer Society show:

  •  Prostate cancer is the leading cause of cancer among Georgia males and accounts for 28 percent of all new cancer cases among males each year.
  • Nationally, about one in six men will be diagnosed with prostate cancer during his lifetime and more than two million men in the United States have been diagnosed with prostate cancer at some point and are still alive today.
  • Other than skin cancer, prostate cancer is the most common cancer in American men and the second leading cause of cancer death, behind lung cancer.

 “It is crucial for men to maintain an ongoing relationship with their healthcare provider as the risk for prostate cancer will vary from person to person,” said Roland Matthews, M.D., from Morehouse School of Medicine and Director of Georgia Cancer Center for Excellence at Grady Health System.

A prostate screening PSA (Prostate Specific Antigen) is a simple blood test which will not define a man’s prostate cancer status, but provides the basis for men to start the right conversations with their doctor.  When prostate cancer is detected early, it is a very curable disease.

To learn more about this prostate cancer initiative, visit www.GeorgiaProstateCancerPledge.com .

Get the Right Test at the Right Time

Monday, November 8th, 2010

Make Your Own Luck

Monday, October 11th, 2010

Five principles for making the most of life’s twists and turns.

By Rebecca Webber 

Mary McGuire-Wien and her husband, Charles Wildbank, had been searching for a new home on Long Island for more than a year, but every place they’d seen was either unsuitable or unaffordable. After one long Sunday of unsuccessful house-hunting with their agent, the couple was anxious to get back home, but got stuck at a traffic light right next to an old barn that was under renovation. “A guy in a hard hat looked over at us and said, ‘Are you looking for a house?’” says Mary.

Though the barn didn’t look like a house—it didn’t even have any visible windows—Mary and her husband got out to take a look. The building turned out to be loftlike, with beautiful historical details (including back-facing windows). “A normal family probably wouldn’t want it,” says Mary. “But it was absolutely perfect for us because we needed a space where I could have a yoga retreat, and where Charles could paint.” They agreed to buy the place from the construction worker, who turned out to be the barn’s owner.

Mary and Charles could be considered fortunate—what are the chances that the owner would stop them when they were most in need of a home? And yet, they were the ones who agreed to investigate an unlikely prospect. Their open-mindedness turned a strange moment into a lucky break.

People who spot and seize opportunity are different. They are more open to life’s forking paths, so they see possibilities others miss. And if things don’t work out the way they’d hoped, they brush off disappointment and launch themselves headlong toward the next fortunate circumstance. As a result, they’re happier and more likely to achieve their goals.

Psychologists are figuring out why some people always seem to juggle incredible opportunities. Their insights can help us all lead luckier lives.

To read about these insights and the rest of the article, click here.

Advancing and Reaching the Disproportionately Affected

Tuesday, September 21st, 2010

African-American men are 60 percent more likely to be diagnosed and 2.4 times more likely to die from prostate cancer. With the stark reality that black men and their families are more more likely to be affected by prostate cancer than any other group of our population, two events provided a fitting end to last week’s Advance on Washington: The African-American Prostate Cancer Health Disparities meeting organized by the Prostate Health Education Network (PHEN) as part of the Congressional Black Caucus meeting, and the Black Barbershop Health Outreach Program (BBHOP) that was held at select barbershops in the Washington and Baltimore metropolitan areas on Saturday. To read the entire article, click here.

From: http://mynewyorkminute.org/

Study: Men With Low Initial PSA Levels Less Likely To Develop Prostate Cancer

Friday, September 17th, 2010

Men with low PSA levels from a baseline blood test were less likely to develop prostate cancer compared to men whose baseline PSA levels were high, according to a new study.

The simple test may be a strong predictor of who will benefit from future screening and treatment for prostate cancer, according to the study published Monday in the journal Cancer.

More than 85,000 men, ages 55 to 74, with no previous prostate cancer history were the subjects of the study. The authors found that in order to save one life, they needed to investigate almost 25,000 men with low PSA levels but only 133 men with high ones. Similarly, they needed to treat 724 men who had low PSA levels to save one life but only 60 men whose levels were higher.

PSA, or prostate-specific antigen, is a protein found in prostate cancer tissue. When that tissue breaks down, the protein seeps into the bloodstream. The heavier the presence of PSA in the blood, the more likely prostate cancer will be dangerous and require some type of treatment, said Dr. Otis Brawley, Chief Medical Officer at American Cancer Society and a contributor to CNNHealth.com.

But aren’t all cancers bad, even if a man’s PSA level is low?

“There are a large number of prostate cancers that don’t need to be treated because they’re not a health threat to the man who has them,” explained Brawley. That makes guidelines for screenings more difficult to set.

The American Cancer Society encourages men to work with their doctors to learn about the test’s benefits and risks before making an informed personal decision around age 50. Research has not yet proven that the potential benefits of testing outweigh the harms of testing and treatment, explains the organization.

The American Urology Association recommends baseline screening for men at age 40 with future screenings determined in conjunction with the patient’s doctor.

“This can’t be done in a vacuum,” said Dr. J. Brantley Thrasher, spokesman for the American Urology Association and the William L. Balk Chair of the Department of Urology at the University of Kansas. “We need to let [patients] know this is an imperfect marker, but we’re getting data that may help us in the future.”

It’s difficult to accept the idea that you could have prostate cancer that doesn’t need to be treated and could be left alone with no harm, while other men have aggressive and deadly prostate cancers. Brawley, who chooses not to be screened, thinks this is why most men get PSA tests regularly, despite the many risks associated treatment.

“By choosing to get screened, there is a guaranteed increase in diagnosis… but there is only a potential decrease in death,” said Brawley.

Some of the risks of treatment include impotence, incontinence and bowel injury.

Still, Thrasher says the importance of the PSA blood test should not be diminished. He tells his patients to get regular screenings every other year or every three years after their initial test.

“I believe knowledge is power to some extent,” said Thrasher. “It’s risks versus benefits… and each decision point is a fork in the road where [me and patients] have to have a discussion.”

From: http://pagingdrgupta.blogs.cnn.com/2010/09/13/study-men-with-low-initial-psa-levels-less-likely-to-develop-prostate-cancer/

September is National Prostate Cancer Awareness Month

Wednesday, August 25th, 2010

It is not surprising that research indicates that men squirm at the thought of modern medicine’s devices probing them for clues to prostate health. There is little discomfort in a Prostate Specific Antigen (PSA) screening. A PSA is a simple blood test that can save a man’s life.

  • One in every six men is diagnosed with prostate cancer.
  • There are about 220,000 new cases of prostate cancer per year.
  • Over 27,050 men will die from prostate cancer.  They were not diagnosed early and treated.

To facilitate a man’s decision on prostate cancer screening or treatment, an informed and shared decision is recommended.  Elements that foster an informed and shared decision include:

  • Balanced, complete information.
  • Advanced age, life expectancy of less than 10 years, or serious medical conditions could be reasons to forgo screening and/or treatment.
  • The individual’s preferences and values regarding cancer, uncertainty, living with impotence, other possible prostate cancer side effects, or other associated issues.
  • Clarity on the level of participation in decision-making the man chooses.
  • A physician who will answer questions, provide balanced sources of information, and give his or her recommendation but ultimately respect the man’s wishes for screening and treatment.

Part of the human toll taken by prostate cancer is the sense typically experienced by newly diagnosed patients of a loss of personal control over their lives. Learn about the diagnosis and the various treatment options available to you.

The Centers for Disease Control and Prevention (CDC) has produced two guides to assist men in making the decision on whether to get screened for prostate cancer.

  1. Prostate Cancer Screening: A Decision Guide
  2. Prostate Cancer Screening: A Decision Guide for African American Men

Both guides are available at no cost through the CDC at:
http://www2.prostrcision.com/e/1174/dcpc-publications-prostate-htm/I5MZC/203883422

Take control of your prostate health.  And help other men do the same!